The Randles Lab is dedicated to applying innovative computational methods to advance the frontiers of biomedical research, gain new insights into complex biological systems, and improve human health. We are passionate about transforming the future of health using massively parallel, personalized, computational simulations of the circulatory system. In particular, we are developing new technologies to enhance the spatial and temporal domains captured in high-fidelity fluid-structure-interaction simulations by efficiently using some of the world's biggest supercomputers. These image-based simulations can yield insight into the underlying mechanisms driving disease progression and inform surgical planning or the design of next-generation drug delivery systems. Working closely with physicians and experimentalists, we establish a tightly coupled feedback loop between the development of the mathematical model and in vivo and in vitro measurements. We are committed to fostering a collaborative and inclusive environment where researchers from diverse backgrounds can tackle challenging problems and share their knowledge and expertise. Our goal is to educate the next generation of biomedical engineers and to contribute to the advancement of healthcare through the development of innovative algorithms and models. We strive to make a meaningful impact in the lives of patients and families by using our expertise in computation to understand and treat diseases better.
*Image created by Madhurima Vardhan, Duke University, and Liam Krauss, Lawrence Livermore National Laboratory.
